AUTHOR=Bakhtiari Sajjad , Timbrell Nathan E. , D’Almeida Sènan M. 

TITLE=Abnormally Low HbA1c Caused by Hemolytic Anemia, a Case Report and Literature Review

JOURNAL=British Journal of Biomedical Science

VOLUME=81

YEAR=2025

URL=https://www.frontierspartnerships.org/journals/british-journal-of-biomedical-science/articles/10.3389/bjbs.2024.13898

DOI=10.3389/bjbs.2024.13898

ISSN=2474-0896

ABSTRACT=<p>Hemoglobin A<sub>1c</sub> is a widely used diagnostic tool for monitoring glycemic control in diabetes management. However, its accuracy can be influenced by various factors. We present a case of a 17-year-old boy with abnormally low Hemoglobin A<sub>1c</sub> levels caused by warm autoantibody-induced hemolytic anemia. This case highlights the importance of considering conditions that may affect erythrocyte survival, and the potential interferences when interpreting Hemoglobin A<sub>1c</sub> results to ensure accurate diagnosis and effective management of diabetes.</p>