AUTHOR=Böhmer Jens , Wasslavik Carina , Andersson Daniel , Ståhlberg Anders , Jonsson Marianne , Wåhlander Håkan , Karason Kristjan , Sunnegårdh Jan , Nilsson Staffan , Asp Julia , Dellgren Göran , Ricksten Anne TITLE=Absolute Quantification of Donor-Derived Cell-Free DNA in Pediatric and Adult Patients After Heart Transplantation: A Prospective Study JOURNAL=Transplant International VOLUME=Volume 36 - 2023 YEAR=2023 URL=https://www.frontierspartnerships.org/journals/transplant-international/articles/10.3389/ti.2023.11260 DOI=10.3389/ti.2023.11260 ISSN=1432-2277 ABSTRACT=
In this prospective study we investigated a cohort after heart transplantation with a novel PCR-based approach with focus on treated rejection. Blood samples were collected coincidentally to biopsies, and both absolute levels of dd-cfDNA and donor fraction were reported using digital PCR. 52 patients (11 children and 41 adults) were enrolled (NCT03477383,