Nanomedicine for Chronic Diseases

Chronic diseases such as cardiovascular disorders, diabetes, neurodegenerative conditions, ocular diseases, and cancer pose significant global health challenges, often necessitating long-term management with limited treatment effectiveness. Conventional therapeutic approaches are hindered by issues such as poor bioavailability, systemic toxicity, drug resistance, and procedural invasiveness. Nanomedicine has emerged as a ground-breaking solution, offering targeted and stimuli-responsive drug delivery strategies, controlled release, and improved therapeutic efficacy. Advances in nanoparticle-based formulations, biomaterials, and nanotechnology-driven diagnostics have opened new frontiers for personalized medicine and improved disease management.

This Special Issue aims to explore the latest developments in nanomedicine for the treatment of chronic diseases, fostering interdisciplinary discussions on innovative therapeutic strategies, clinical translation, and future prospects. The objective is to highlight cutting-edge research that can lead to new prevention, diagnostic, and treatment methodologies. The goal is to bring together experts in nanotechnology, pharmaceutical sciences, and medicine to discuss novel nanoparticle formulations, targeted and stimuli responsive drug delivery systems, theranostics, and nanotechnology-enabled regenerative medicine. We welcome contributions that address key challenges in clinical translation, biocompatibility, large-scale manufacturing, and regulatory affairs. By bringing together insights from researchers and industry leaders, this Special Issue seeks to bridge the gap between fundamental research and real-world applications, ultimately improving patient outcomes.

We welcome contributions covering a broad spectrum of nanomedicine applications for chronic diseases, including but not limited to the following topics:
• Nanoparticle-based drug delivery strategies
• Targeted and stimuli-responsive nanocarriers
• Nanomedicine applications in oncology, neurology, cardiology, ophthalmology, and metabolic disorders
• Innovations in nanodiagnostics and biosensing technologies
• Clinical translation and regulatory challenges in nanomedicine
• Biocompatibility and toxicity evaluation of nanomaterials
• Nanotechnology-driven regenerative medicine and tissue engineering

We encourage submissions exploring nanoparticle-based drug delivery, targeted and controlled-release systems, theranostics, nanodiagnostics, and regenerative medicine, with a focus on advancing therapeutic efficacy and clinical applicability. Additionally, submissions discussing challenges in clinical translation, large-scale manufacturing, biocompatibility, and regulatory considerations are encouraged. We invite articles that provide novel insights into the application of nanomedicine in areas such as oncology, neurology, cardiovascular diseases, metabolic disorders, ocular diseases, and autoimmune conditions. Submissions focusing on preclinical and clinical advancements, novel nanocarrier designs, biomaterials, and personalized medicine approaches are also welcome. Authors from interdisciplinary backgrounds, including life sciences, nanotechnology, pharmaceutical sciences, medicine, and biomedical engineering, are encouraged to contribute. This Special Issue aims to serve as a platform for cutting-edge research that bridges the gap between laboratory innovations and real-world clinical applications.

Article types and fees

This Special Issue accepts the following article types, unless otherwise specified in the Special Issue description:

• Brief Research Report
• Editorial
• Mini Review
• Original Research
• Perspective
• Review
• Systematic Review
• Technology and Code

Articles that are accepted for publication by our external editors following rigorous peer review incur a publishing fee charged to Authors, institutions, or funders.

Article types

This Special Issue accepts the following article types, unless otherwise specified in the Special Issue description:

• Brief Research Report
• Editorial
• Mini Review
• Original Research
• Perspective
• Review
• Systematic Review
• Technology and Code

Keywords: Nanomedicine, drug delivery, chronic disease, cardiovascular disorders, diabetes, cancer, neurodegeneration, ocular diseases